353 West 22nd Street

353 West 22nd Street — Historic Two-Unit Townhouse with Modern Upgrades
Tucked away on one of Chelsea’s most charming tree-lined streets, this exquisite 19th-century townhouse offers the rare opportunity to own a piece of history. Currently configured as a two-unit residence, this home offers the flexibility to be seamlessly converted into one home.
Refined and soulful, the residence spans five stories and has been tastefully reimagined into two independent homes—each with a distinct personality, generous proportions, and updated interiors that honor the home’s architectural roots.
The garden duplex is a serene two-bedroom, two-bathroom sanctuary with a lush, professionally landscaped backyard featuring flagstone pavers, a custom gazebo, and ample space for entertaining or unwinding outdoors. The layout flows gracefully from a private entrance into an airy living area with soaring ceilings, exposed brick, and a lofted space that adds drama and dimension. Both bedrooms offer generous storage and easy access to two renovated bathrooms.
The upper triplex is a spacious four-bedroom, two-bath residence flooded with natural light from oversized windows and a dramatic skylight above a spiral staircase. A large kitchen anchors the formal living and dining rooms while king-sized bedrooms and ample closets provide practical comfort.
Timeless architectural details—including six original fireplace mantels, ceiling medallions, crown moldings, custom built-ins, and hardwood floors—are thoughtfully preserved throughout. Behind the walls, key upgrades such as a new boiler, roof, and renovated kitchens and baths ensure modern comfort.
Built in 1874 for a prominent Scottish émigré pharmacist, this historic home was once the residence of stage actress Clara Louise Thompson. Located moments from the High Line, Chelsea Market, and Manhattan’s premier art galleries and dining, 353 West 22nd Street is a home of enduring beauty, remarkable flexibility, and rich cultural provenance.